Sickle Cell Disease Concept Essay
Sickle Cell Disease Concept Essay
Introduction
Sickle cell disease (SCD) is a major health concern in the United States. According to Akingbola et al. (2016), the introduction of hydroxyurea (HU) was a major relief to patients as it has been proven to alleviate symptoms of the disease. Adewoyin, Oghuvwu, and Awodu (2017) argue that this mode of managing SCD is yet to be universally embraced by medical practitioners in the country. Some still believe in other forms of medication. Research has proven that this form of managing SCD helps in prolonging the life of a patient by protecting vital organs and reducing pain (Sandhu & Cohen, 2015).Sickle Cell Disease Concept Essay
Background of the Problem
Sickle cell anemia is an inherited health problem that medical researchers have been working tirelessly to find ways of managing. The first case of a sickle cell anemia patient was recorded in 1910 (Sandhu & Cohen, 2015). Walter Noel, a dental student in Chicago, went to the hospital complaining of episodic pains and signs of anemia. Dr. Ernest Irons examined the blood and noticed that his red blood cells had the shape of a sickle (Adewoyin et al., 2017). Working closely with Dr. James Herrick, they were able to examine the condition and discovered that it was a complex health problem, which medical experts had not encountered (Sandhu & Cohen, 2015). Since then, a lot of research and tests have been conducted to find the best way of dealing with the problem.Sickle Cell Disease Concept Essay
Theoretical Foundations
Theoretical models may help in explaining the relevance of HU among SCD patients and the manner in which both practitioners and patients can be convinced to embrace it. The Health Belief Model (HBM) is one of the most appropriate theories that can be used in this project. Adewoyin et al. (2017) define HBM as “a psychological model that attempts to explain and predict health behaviors” (p. 258). This theory is based on three main concepts.
The first concept is that a person is likely to take a health-related action if he or she believes that doing so will avoid negative health consequences. The second concept is that one is likely to take appropriate action if the person has a positive expectation that when a recommended action is taken, a negative health condition would be avoided (Sandhu & Cohen, 2015). The last concept is that one will be motivated to take a health-related action if he or she has the right knowledge on how to take a specific action.Sickle Cell Disease Concept Essay
The theory will be relevant in this project because it outlines strong reasons why it is necessary to popularize the use of HU when dealing with SCD patient. As explained above, the perception that people have towards a given mode of therapy defines whether they will embrace it. When a patient is convinced that this method will alleviate the symptoms and reduce pain, he or she will demand it. The pressure from patients will push doctors to embrace this mode of medication. The theory also emphasizes the importance of understanding how a given treatment method words for it to be acceptable. Doctors can only embrace the new method if they understand the manner in which it works and the possible consequences. Sandhu and Cohen (2015) explain that in many cases, doctors are keen on avoiding methods that they have not used before for fear of making mistakes.Sickle Cell Disease Concept Essay
Reviewing relevant literature helps in identifying the main themes that will be the primary focus of the study. In this section, the researcher has identified three main themes that will be discussed further when conducting the study.
Patients’ Perceptions of HU Efficacy
The perception of patients towards HU efficiency determines whether they will request for it or not. The following factors have a direct impact on patients’ perception towards HU.
Information from medical experts
According to Sandhu and Cohen (2015), the information that patients receive from experts has a direct impact on their beliefs. If experts popularize this form of medication as being effective, patients will trust it.Sickle Cell Disease Concept Essay
Information from colleagues
Information that patients receive from colleagues suffering from similar complications affects their trust. When these colleagues attest to the effectiveness of the drug, these patients will be motivated to embrace it
Patient’s experiences
Patients who have received the medication before are likely to form an opinion based on their experience (Keikhaei, Yousefi, & Bahadoram, 2016). If the medication alleviated the symptoms before, they would support its use.Sickle Cell Disease Concept Essay
HU’s Impact on Organ Damage
According to Sandhu and Cohen (2015), proper use of HU reduces organ damage among patients suffering from sickle cell disease. The following are some of the ways in which this medication helps to protect these organs.
Ability to increase fetal hemoglobin levels
A study by Lebensburger, Grosse, Altice, Thierry, and Ivankova (2015) revealed that HU could increase fetal hemoglobin. In so doing, the blood can transport necessary nutrients to sensitive body organs, ensuring that they remain healthy.Sickle Cell Disease Concept Essay
Decrease the severity and frequency of SCD exacerbations
SCD exacerbations have a direct negative impact on the heart of patients suffering from sickle cell disease. However, this medication could reduce the severity and frequency of SCD exacerbations, which in turn helps in protecting the heart (Tafrali et al., 2013).
Motivating regular check-ups
Patients who embrace HU are often motivated to conduct regular tests to ensure that they remain healthy when taking the medication. Regular tests make it possible to identify if any of the vital organs is affected. Early diagnosis makes it easy to address the problem (Fitzhugh et al., 2015).
Increase in Patients’ Life Expectancy
The primary goal of these new methods of managing sickle cell disease is to ensure that patients’ life expectancy is prolonged. Eliminating pain associated with symptoms of this disease is not enough (Milosevic, Levy, Alcolado, & Radomsky, 2015). The following are some of the ways in which HU can help prolong lives of patients suffering from SCD.Sickle Cell Disease Concept Essay
Decrease the frequency of pain episodes in patients
Some of the symptoms of SCD are often accompanied by severe pain. HU is known to eliminate such pain, making life more meaningful. Matt and Matthew (2013) argue that some patients often consider taking their own lives because of such cases of extreme pain. Eliminating the pain prolongs the life of the patient.
Prevent various life-threatening complications
As explained in the section above, HU helps in protecting vital body organs such as the heart. Eliminating these life-threatening complications such as heart failure prolongs the life of a patient suffering from SCD (Wang et al., 2013).
Regular medication
Patients who are enrolled in this HU programs are often encouraged to take regular medication as a way of combating their condition. Maintaining regular medication helps in suppressing symptoms of SCD (Tafrali et al., 2013). Such a patient is more likely to lead a near-normal lifestyle than their colleagues who are not maintaining regular medication.
Problem Statement
It is not known by many medical practitioners and patients that Hydroxyurea is an effective method of managing sickle cell disease. Although studies have revealed the effectiveness of this form of therapy, it is yet to be widely embraced as the most appropriate medication for patients with sickle cell disease. It is necessary to undertake this project because it focuses on the promotion of this form of medication when managing SCD.Sickle Cell Disease Concept Essay
It will address some of the doubts that some of the practitioners have about the usefulness of HU. If it is embraced, this new method will benefit the entire population of those with SCD not only in the United States but also in other parts of the world. The project will help in solving the problem of uncertainty among practitioners when it comes to using HU to manage SCD.
Purpose of the Project
The purpose of this project is to investigate if taking hydroxyurea by adults aged 18-30 who are diagnosed with sickle cell disease decreases sickle cell crisis (SCC) severity. The study was to be conducted within a period of six weeks. To achieve this goal, the researcher intends to conduct quantitative research with a retrospective chart review. Of interest will be to determine the number of respondents who believe that using HU can significantly improve the condition of an SCD patient as opposed to embracing the other existing methods.Sickle Cell Disease Concept Essay
The chosen design will make it possible to present the findings made using relevant graphs and charts for clarity. It will be easy to determine the benefits of this medication by statistically comparing the level of improvement made by those who take HU and those who do not. The outcome will help clarify the significance of this method of managing sickle cell disease. The project will specifically affect patients with sickle cell disease and all practitioners who are responsible for offering them medical services.
To the patients, the project will help in determining a better medication that can prolong their lives and eliminate adverse effects of SCD. To the medical practitioners, the report will provide a better way of dealing with SCD in a way that reduces cases of hospital readmissions. The project will make an important contribution in this field by providing evidence of the effectiveness of a new method of managing SCD.Sickle Cell Disease Concept Essay
Clinical Questions and Variables
According to Tafrali et al. (2013), developing an effective research question is critical when planning to conduct research. The question defines the data that is to be collected to meet goals and objectives of the study. A properly structured question should capture the primary aim of research. As such, it was necessary to develop an appropriate question to be used in this project. The researcher developed the following PICOT question to help in conducting the investigations.
In adults (aged 18-30) diagnosed with Sickle Cell Disease (SCD), does taking Hydroxyurea compared to those not taking Hydroxyurea decrease Sickle Cell Crisis (SCC) severity over a six- week period?
The affected population (P), as shown in the question above, is patients diagnosed with sickle cell anemia aged 18-30 years. These young, energetic adults are expected to play leading roles in the country’s economic growth. When they are affected by this problem, their productivity is significantly reduced. Taking Hydroxyurea is the intervention (I) plan. It is believed that taking this medication may help improve the condition of a patient with SCD. The intervention does not only eliminate the pain but also protects vital organs within the body, increasing the patient’s life expectancy.
The comparison (C) is not taking HU among patients suffering from sickle cell disease. The analysis will try to compare the condition of a patient who takes this medication with that of a patient who does not. The comparison will provide the needed proof that taking HU is significantly important for patients with SCD. Decreasing the severity of sickle cell crisis if the outcome (O). It is expected that this intervention will have a positive impact on the affected group as discussed above.Sickle Cell Disease Concept Essay
The medication should be scientifically proven to offer the expected therapeutic relief to the patient. Finally, the time (T) set for the outcome to be evident is six months. The period is long enough to enable the medication to have the desired impact on the patient while at the same time being short enough to make it possible to complete the project within the set time. The outcome of the study will inform the practice by determining the relevance of HU among SCD patients.Sickle Cell Disease Concept Essay
